http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102533996-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d0451e593692e9996ee1672449fb2fe |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2012-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9924c38546c9c42cb78355b4a9d916c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee5046330536e5b6d7d19ee0de25cf95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16713cfa403438b239acf4ae114ae89d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62d5c268a29646b9806bdce9e763c693 |
| publicationDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102533996-B |
| titleOfInvention | Method for determining APRIL (A Proliferation-inducing Ligand) gene promoter and transcription factor binding site and use |
| abstract | The invention discloses a method for determining an APRIL (A Proliferation-inducing Ligand) gene promoter and transcription factor binding site and use. According to the invention, a promoter region of APRIL is cloned and identified. As discovered, a region from -1539 to -1001 has an important effect on transcription adjustment and control over APRIL; a transcription factor Sp1 or NF-kB exits in the region; and the transcription of the APRIL gene can be activated. The invention provides application of mithramycin and Bay11-7082 to preparation of medicaments for treating human colorectal adenocarcinoma; and the effect is clear. |
| priorityDate | 2012-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.