http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102533948-B

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_767b2f19da181d5fb2de3b35f3d7956d
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee4d6ccc1123adb11bb3e9b4281fb8ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0343f4441576c84a8a218105bedfeb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5155ebc5c242572e3db0edd71f728e9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391700df16e5193f5aeca59126da8cc5
publicationDate 2014-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102533948-B
titleOfInvention apoB (apolipoprotein B) gene SNP (Single Nucleotide Polymorphism) detection specific primer and liquid-phase chip
abstract The invention discloses an apoB gene SNP (Single Nucleotide Polymorphism) detection specific primer and liquid-phase chip. The liquid-phase chip comprises an ASPE (Allele Specific Primer Extension) primer, microspheres and an amplification primer, wherein the ASPE primer consists of a tag sequence at 5' end and specific primers aiming at target gene mutation at 3' end, wherein the specific primers are SEQ ID NO. 12 and SEQ ID NO. 13 aiming at a C181T SNP site, SEQ ID NO. 14 and SEQ ID NO. 15 aiming at a C245A SNP site, SEQ ID NO. 14 and SEQ ID NO. 15 aiming at a C245T SNP site, SEQ ID NO. 17 and SEQ ID NO. 18 aiming at a G153A SNP site, SEQ ID NO. 19 and SEQ ID NO. 20 aiming at a G82A SNP site, and/or SEQ ID NO. 21 and SEQ ID NO. 22 aiming at a G62A SNP site; and the microspheres are coated by anti-tag sequence. The matching ratio of the detection result of the apoB gene SNP detection liquid-phase chip provided by the invention and that of a sequencing method reaches up to 100 percent; and parallel detection of a plurality of polymorphic sites is realized.
priorityDate 2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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