http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102532218-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706
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filingDate 2011-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f924a40ae8c6d85fae0169462803ec2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abe1e11ef244362285ee5f1dbc7a82a7
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publicationDate 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102532218-B
titleOfInvention Strictosidine-like alkaloid as well as preparation method and application thereof
abstract The invention provides a strictosidine-like alkaloid and a pharmaceutically acceptable salt (I) of the strictosidine-like alkaloid. According to the invention, a target compound is prepared from a 2-(1-indol)-ethylamine derivative and diffractive ring strychnine in the presence of immobilized strictosidine synase. The in vitro cytotoxicity experiment of the compound provided by the invention indicates that the compound has inhibition action on K562 tumor cell growth and can be applied to preparation of a medicine for preventing and treating human chronic myelogonium leukemia. The general formula of the compound is shown in the specification.
priorityDate 2011-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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