http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102532218-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 |
filingDate | 2011-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f924a40ae8c6d85fae0169462803ec2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abe1e11ef244362285ee5f1dbc7a82a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69d66e6456dd13690f02ba9a794d6c4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_250edff37a0b3c11eadb7f2ba56b8b0a |
publicationDate | 2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102532218-B |
titleOfInvention | Strictosidine-like alkaloid as well as preparation method and application thereof |
abstract | The invention provides a strictosidine-like alkaloid and a pharmaceutically acceptable salt (I) of the strictosidine-like alkaloid. According to the invention, a target compound is prepared from a 2-(1-indol)-ethylamine derivative and diffractive ring strychnine in the presence of immobilized strictosidine synase. The in vitro cytotoxicity experiment of the compound provided by the invention indicates that the compound has inhibition action on K562 tumor cell growth and can be applied to preparation of a medicine for preventing and treating human chronic myelogonium leukemia. The general formula of the compound is shown in the specification. |
priorityDate | 2011-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.