http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102525990-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
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filingDate 2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2c7f3127373b7ad5c628b671fd5bace
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9096ee410464e4bbe1b883117c9c252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9112e37d9225313ab611198c69288ac
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publicationDate 2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102525990-B
titleOfInvention Ilaprazole enteric-coated tablets and preparation method thereof
abstract The invention provides ilaprazole enteric-coated tablets and a preparation method thereof. Each enteric-coated tablet contains an enteric-coated pellet and pharmaceutically acceptable tablet excipients, wherein the enteric-coated pellet contains a pellet layer, a medicine loading layer, an isolation layer and an enteric coating layer; and the medicine loading layer contains ilaprazole or pharmaceutically acceptable salt thereof and a stabilizer. The enteric-coated pellet tablets prepared from the ilaprazole have good acid resistance; barrier substances such as an antiacid, a surfactant, an organic solvent, a hydrophobic substance and the like are not contained in the prescription, so that the enteric-coated pellet tablets have health benefits and are safe; the preparation method is easy to operate, the organic solvent is not used, and an active substance is quickly and stably released; and in addition, the pellets in the tablets can be widely and uniformly distributed in an intestinal tract after being taken, the dose dumping is dispersed, and the distribution area of a medicine on the surface of the intestinal tract is increased, so the irritation of the medicine to the intestinal tract can be reduced or eliminated, and the bioavailability of the medicine can be improved.
priorityDate 2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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