http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102525936-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e26a9336e3636c9da9236bc044e2e2aa |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2012-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b756192ad03d774fd921c77200e6ff6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b082ff89720f57fa2b8273f66f3661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85921fcc214a730678bc9359f9f9dbae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_292473a542b83288de4b3f14955fe08f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d676d44922efda904797b5c29a2d356 |
publicationDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102525936-B |
titleOfInvention | Compound epirubicin hydrochloride polylactic-co-glycolic acid (PLGA) nanoparticles and preparation method thereof |
abstract | The invention relates to a compound anti-tumor nanoparticle preparation and a production technology thereof, in particular to a compound epirubicin hydrochloride polylactic-co-glycolic acid (PLGA) nanoparticles and a preparation method thereof. In order to overcome the defects that the in vivo retention time of epirubicin hydrochloride and gadopentetate dimeglumine is short and the treatment effect is inconvenient to observe, the epirubicin hydrochloride and the gadopentetate dimeglumine are used together to prepare the compound nanoparticle preparation containing the epirubicin hydrochloride and the gadopentetate dimeglumine, so that the medicine can stay at the tumor position for a long time and release, and the anti-tumor effect can be detected in real time. The therapeutic medicine with the detection function has wide clinical application prospect. Due to the compound epirubicin hydrochloride nanoparticles, a basis is laid for application of the nanoparticle preparation with the detection medicine to clinical treatment on liver cancer and the like. |
priorityDate | 2012-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.