| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01d74e1f4b646c6f83d40ae812413f8f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
| filingDate |
2011-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57322ce2d94966ed48b19544c3db61aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8701af215a5ad8627d1b0846817a78b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cddef0d4813141a29258b985b73d3623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfa35cb9e55c1d7afdccb38a99fccdb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_867990c7c184e64c2049ef0107e7ba23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d63b9c07398e2c24ef5e6807fceef83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40deef36790a8f7b4a8b08eccdcc47bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2f0d4e229ab49b6e92da3531e3e963
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71c6a4bd67cfdc7a1731ccebdd767150
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fd4ffd269d912749adc25284e151a55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2336e8eb5f734bf1e3faa4f9816c8b9 |
| publicationDate |
2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102492038-B |
| titleOfInvention |
Anti-human Tim-3 neutralized monoclonal antibody L3D and application thereof |
| abstract |
The invention discloses an anti-human Tim-3 neutralized monoclonal antibody L3D and an application thereof. Antibody light and heavy chain variable region genes are cloned from a prepared anti-human Tim-3 neutralized monoclonal antibody L3D hybridoma cell; and the obtained light chain and heavy chain variable region genes can be used for encoding a monoclonal antibody variable region. Based on the light and heavy chain variable region genes of the monoclonal antibody, a plurality of small molecular genetic engineering antibodies can be constructed and expressed. Polypeptides or proteins encoded on the basis of the genes can be cross-linked with a plurality of bioactive molecules, so that a Tim-3 expression level detection reagent is prepared for diagnosing and treating diseases caused by abnormal expression of Tim-3. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017205721-A1 |
| priorityDate |
2011-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |