http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102488920-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50
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filingDate 2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7dcccf274240cb926bd3b1b30a2549
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publicationDate 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102488920-B
titleOfInvention Alpha-calcium sulfate hemihydrate/hydroxyapatite composite granule with nuclear shell structure and preparation thereof
abstract The invention discloses an alpha-calcium sulfate hemihydrate/hydroxyapatite composite granule with a nuclear shell structure and preparation thereof. The composite granule has a microstructure in which the hydroxyapatite wraps the alpha-calcium sulfate hemihydrate. The preparation method comprises the steps of: using deionized water as a solvent, dissolving a proper dosage of organic crystal modifier and inorganic salt crystal modifier, adding calcium sulfate dehydrate and hydroxyapatite, and performing hydrothermal synthesis under certain technical parameters. According to the invention, the alpha-calcium sulfate hemihydrate and the hydroxyapatite are compounded in the microstructure so as to adjust the quick consolidation defect of pure alpha-calcium sulfate hemihydrate to improve the injection performance thereof, and a microstructure with a controllable wrapping degree can be formed to adjust and control the biodegradation performance thereof, so that the composite granule has a brilliant clinical application prospect.
priorityDate 2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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