http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102488920-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 |
filingDate | 2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7dcccf274240cb926bd3b1b30a2549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9b67eba74cd21ba30fd9dff2b18c4a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de67d0910354bdf34911683f9dabf871 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5160124b7ed5e23b00c681e8e54db280 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e45a0befb1adf25e1e5803f4299b7280 |
publicationDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102488920-B |
titleOfInvention | Alpha-calcium sulfate hemihydrate/hydroxyapatite composite granule with nuclear shell structure and preparation thereof |
abstract | The invention discloses an alpha-calcium sulfate hemihydrate/hydroxyapatite composite granule with a nuclear shell structure and preparation thereof. The composite granule has a microstructure in which the hydroxyapatite wraps the alpha-calcium sulfate hemihydrate. The preparation method comprises the steps of: using deionized water as a solvent, dissolving a proper dosage of organic crystal modifier and inorganic salt crystal modifier, adding calcium sulfate dehydrate and hydroxyapatite, and performing hydrothermal synthesis under certain technical parameters. According to the invention, the alpha-calcium sulfate hemihydrate and the hydroxyapatite are compounded in the microstructure so as to adjust the quick consolidation defect of pure alpha-calcium sulfate hemihydrate to improve the injection performance thereof, and a microstructure with a controllable wrapping degree can be formed to adjust and control the biodegradation performance thereof, so that the composite granule has a brilliant clinical application prospect. |
priorityDate | 2011-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.