http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102488655-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc0c59e220d087146bcbd3dd07a72c1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8284feba73620182140a149e8295e7d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc4ed35421ec99315e45bde851567917 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c14b02bbf8f81531593a03116c9a0f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_826a8ee7c95aeb80ab36eb89d837447a |
| publicationDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102488655-B |
| titleOfInvention | N3-ortho toluene formoxyl uracil nanosuspension and lyophilized preparation thereof |
| abstract | The invention discloses N3-ortho toluene formoxyl uracil nanosuspension and lyophilized preparation thereof, which belong to the technical field of medical drugs. The preparation method of the lyophilized preparation of the N3-ortho toluene formoxyl uracil nanosuspension comprises the steps of (1) dispersing surface active agents into water solution to obtain solution A; (2) dispersing N3-ortho toluene formoxyl uracil into the solution A to obtain injectable suspension B; (3) shearing the injectable suspension B at high speed to obtain foremilk C; (4) enabling the quality of the foremilk C to be even through a milk evening machine to obtain the N3-ortho toluene formoxyl uracil nanosuspension; and (5) adding lyophilized protective agents into the nanosuspension, filtering and degerming, lyophilizing and drying to remove water, and obtaining the lyophilized preparation of the N3-ortho toluene formoxyl uracil nanosuspension. The nanosuspension prepared by the preparation method is uniform in appearance quality with average grain diameter of 50-200nm, high in dissolution rate and capable of being prepared into injection or oral preparation of tablets, capsules and the like in special application. |
| priorityDate | 2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.