abstract |
Present disclose provides antibody, including the monoclonal antibody separated, it specifically combines cadherins 17 with high-affinity.Additionally provide the nucleic acid molecules of coding cadherins 17 antibody, for expressing the expression vector of cadherins 17 antibody, host cell and method.Additionally provide bispecific molecule and the pharmaceutical composition comprising cadherins 17 antibody.Disclose the method for detecting cadherins 17, and be used for treating various cancer, including colorectal carcinoma, method. |