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filingDate 2010-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff88b54d30dfe273459bf45aa3c6b9ed
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publicationDate 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102480959-B
titleOfInvention Benzoic acid conjugates, benzoic acid derivative conjugates and heteroaryl carboxylic acid conjugates of hydrocodone and their prodrugs, preparation methods and uses
abstract The present application provides compositions comprising an aryl carboxylate chemically conjugated to hydrocodone (4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-one) Acids, thereby forming novel prodrugs/compositions of hydrocodone, said aryl carboxylic acids including benzoic acid and heteroaryl carboxylic acids, said compositions having reduced abuse potential of hydrocodone. The present application also provides methods of treating patients, pharmaceutical kits, and methods of synthesizing the conjugates of the present application.
priorityDate 2009-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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