http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102477014-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-417 |
| filingDate | 2010-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102477014-B |
| titleOfInvention | The preparation method of Peremin |
| abstract | The present invention relates to a kind of industrial production process of medicinal rank Peremin, using methyl-cyclohexanol as reaction solvent, Histidine is suspended in this solution, after 170 DEG C ~ 175 DEG C decarboxylic reactions, the methyl cyclohexane alcoholic solution containing spirit of salt is quantitatively dripped, synthesis Peremin by twice.Peremin related substance < 0.5% prepared by the present invention, single contaminant < 0.1%, meet medicinal rank completely, and equipment is simple, technological operation is easy, reacts safe and reliable, recycled solvent, environmental friendliness, is beneficial to industrial mass production. |
| priorityDate | 2010-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.