http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102464610-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a08e2195b3df456a4567304dbd6eba01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af64e661135ea6c4ecdeb1c4b7205b98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa12caaf02b4820c19289f80ceb49116 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 |
| filingDate | 2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08fe6ce9d77325f104cddc434d55c020 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c33d9715bedbacd143915fd31b8d1d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7e9aabdbcc408892866ed97a05b5347 |
| publicationDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102464610-B |
| titleOfInvention | Preparation method of metyrapone |
| abstract | The invention provides a preparation method of metyrapone. The preparation method comprises the following steps of: reacting 3-acetylpyridine with Mg powder in an organic solvent under the action of a catalyst; hydrolyzing to obtain 2,3-bipyridine-3-radical-2,3-butanediol; undergoing a rearrangement reaction on the 2,3-bipyridine-3-radical-2,3-butanediol under the action of a strong acid to obtain crude metyrapone; and recrystallizing to obtain metyrapone as a finished product. The preparation method has the advantages of short process flow, easy and convenient operating, higher yield and easy control over the quality of the finished product, and is suitable for industrial production. |
| priorityDate | 2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.