| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8281ac9f4fb11f15a5da018344453338 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0808
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-21 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 |
| filingDate |
2010-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cb464ce0f2cde3f4f0952eb883f9197
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cb81949eaeac96aa80769504040121c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df14aeca6fd391e1778524574b94de79 |
| publicationDate |
2012-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102458444-A |
| titleOfInvention |
Macrocyclic compounds useful as hepatitis C virus inhibitors |
| abstract |
The present invention discloses a compound of formula I or a pharmaceutically acceptable salt, ester, or prodrug thereof: It has serine protease inhibitory activity, especially inhibits hepatitis C virus (HCV) NS3-NS4A protease activity. Therefore, the compounds of the present invention disturb the life cycle of hepatitis C virus and can also be effectively used as antiviral agents. The present invention further relates to a pharmaceutical composition comprising a compound as described above for administration to a subject suffering from hepatitis C virus (HCV) infection. The present invention also relates to methods of treating hepatitis C virus (HCV) infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107266529-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107074876-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017173960-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107074876-A |
| priorityDate |
2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |