http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102443055-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2011-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102443055-B |
titleOfInvention | A kind of purifying process of recombinant soluble human TRAIL |
abstract | The invention discloses the new purifying process of recombinant soluble human TRAIL.The present invention is chromatographed using Zinc Ions Chelated, two step hydrophobic chromatographies are with regard to that can obtain the recombinant soluble human TRAIL that purity is high, bioactivity is good.The present invention needs the characteristics of zinc ion maintains its tertiary structure and bioactivity using recombinant soluble human TRAIL, is chromatographed using Zinc Ions Chelated, it is to avoid remain using caused by other metal ionsï¼›Using hydrophobic chromatography rather than ion exchange, it is to avoid recombinant soluble human TRAIL solubility under low-salt conditions is smaller and the problem of need to dilute at high proportion, while the step of eliminating ultrafiltration desalination. |
priorityDate | 2011-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.