http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102443000-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_078cb8366425c7f7bb46338421d23406 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
| filingDate | 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2106f6921528ffcfc05274eea1d196e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2556a037ba93caa0c1ce57b9fa81bc2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbcc4160dd81edbaed0e7d1775a62814 |
| publicationDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102443000-B |
| titleOfInvention | Preparation method of iloperidone |
| abstract | The invention provides a preparation method of iloperidone. The method of the invention comprises reacting 2, 4-difluorophenyl(4-piperidyl) ketoxime and 4-chloropropoxy-3-methoxyacetophenone in an aqueous solution of an alkali metal hydroxide, with the concentration of the alkali metal hydroxide maintained at 20-40%. The method provided in the invention has the advantages of simple process, easy operation, high overall yield, and no generation of compound hard to separate during preparation, and can obtain a qualified finished product through simple recrystallization as well as has no need for purification by column chromatography, thus being suitable for industrial production. |
| priorityDate | 2010-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.