http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102440962-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9683e667c2fc35e99047b5a77fea519c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1287544b9b5051ffcd36748f643a940 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e196de8b2ca62b860fc66706366ae45b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20ed2841423d785fd1b41341f4ef916c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c22e3e49d839efc25fd22879767120c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4c764e92a73c0701341cb54332e0bb9 |
| publicationDate | 2015-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102440962-B |
| titleOfInvention | Paeonol micro depot carrier and method for enhancing oxidation resistance of paeonol |
| abstract | The invention relates to a paeonol micro depot carrier and a method for enhancing oxidation resistance of paeonol. Paeonol is insoluble in cold water, has a special smell and can be easily oxidized, thereby greatly restricting the application range of the paeonol as a medicine. An in-situ coagulation method is utilized to coat the paeonol in a micro depot carrier. The in-situ coagulation method comprises the following steps: dissolving 0.5-4.0 parts of gelatin and 0.5-4.0 parts of sodium alginate in water to obtain a solution; adding 1-6 parts of paeonol into the solution obtained in the first step, heating to 55-60 DEG C, and carrying out high-shear emulsification to obtain a stable O/W emulsion; dropwisely adding a 5-10% acetate solution to obtain a suspension; and adding 0.01-0.2 part by weight of 1-5% calcium chloride solution to cure a coagulum, cooling in an ice bath to below 5 DEG C, filtering, adding 0.15-0.5 part by weight of anticoagulant magnesium aluminum silicate into the filter cake to disperse the filter cake, and drying under reduced pressure to obtain the paeonol-containing micro depot carrier powder. The invention is applicable to the field of medicine. |
| priorityDate | 2011-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.