Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2009-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb02ccd5b417a3f2ef859e19afdb4429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4845a36db9dc07cee2eecd000593453e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_756b5d61411c389ce0f4adfd05eb3d0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e90e2d5d096aea98eda5d3cb52d892b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b65845e515d80f674b2241eef440752d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f68b14257b09ad91e3deb7d79807fb43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3cf5488036a6e17bbf70a56fd00f167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e927d1079d2318fdfbc87fb041be4010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a2034bd7e079b6b31f1bac4bb9722fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa39bcb2b23b98859a97bfee91080d02 |
publicationDate |
2014-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-102439169-B |
titleOfInvention |
Compositions and methods for micro-rna expession profiling of colorectal cancer |
abstract |
The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer, the kit comprising a plurality of nucleic acid molecules, each nucleic acid molecule encoding a miRNA sequence, wherein one or more of the plurality of nucleic acid molecules are differentially expressed in the target cells and in one or more control cells, and wherein the one or more differentially expressed nucleic acid molecules together represent a nucleic acid expression signature that is indicative for the presence of or the predisposition to develop colorectal cancer.; The invention further relates to corresponding methods using such nucleic acid expression signatures for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer as well as for preventing or treating such a condition. Finally, the invention is directed to a pharmaceutical composition for the prevention and/or treatment of colorectal cancer. |
priorityDate |
2008-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |