http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102432973-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L51-00 |
| filingDate | 2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102432973-B |
| titleOfInvention | One class microballoon used for high-throughput drug screening and preparation method thereof |
| abstract | The present invention discloses class microballoon used for high-throughput drug screening and preparation method thereof, wherein containing：150 600 parts of polystyrene, 38 part of first functional monomer, 14 part of second functional monomer, 0.1 0.9 parts of fluorescent materials and 0.5 5 parts of chitosans.The microballoon that the present invention is provided, which is met, closes on scintillation analysis method (SPA) requirement in high-flux medicaments sifting, its particle size is in 37 μm, uniformity U ＜ 0.3 (U values are smaller, illustrate that its particle diameter distribution is narrower).Contain amino, carboxyl and hydroxyl in the chitosan of microsphere surface, the amino that these can be with protein, carboxyl and other group covalent bonds or electrostatical binding.In addition, chitosan can form parent/hydrophobic region in microsphere surface, while the biocompatibility of chitosan is good, so as to avoid the conformational change of protein during screening, screening quality and efficiency can be improved with protein formation hydrophobic effect. |
| priorityDate | 2010-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.