http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102432783-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc4e13141d402ceb885f368dfa042348 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ff9c51e1a6141702739f52a07cda15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80936adc866b5a034a052d40c47edf2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1fd3b1dcd9b608b7b7374c2d5f1eead http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6320eada9af489abffbc84678d444f93 |
| publicationDate | 2013-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102432783-B |
| titleOfInvention | PH response/hydrophobic group random copolymerization polymer, and preparation method and application thereof |
| abstract | The invention discloses a pH response/ hydrophobic group random copolymerization polymer, and a preparation method and application thereof. A hydrophobic group and pH response group random copolymer is obtained through electron transfer activator regeneration-atom transfer radical polymerization and ring-opening polymerization, and a pH response amphiphilic polymer brush is prepared by triggering the activators regenerated by electron transfer (ARGET) atom transfer radical polymerization (ATRP) of hydrophilic macromolecule monomers by the hydrophobic group and pH response group random copolymer used as macroinitiator, and performing selective hydrolysis reaction. The proportion of functional groups in the polymer molecule is easy to adjust and control; and a synthesis process is simple and the yield is high. Polymer micelle with an inner core formed by hydrophobic groups and a pH response groups, and an outer shell formed by hydrophilic groups can be obtained by a dialysis method; and a water insoluble medicament can be entrapped in the inner core of the micelle, the medicament can be subjected to sustained release in gastric juice, and can be released quickly and controllably under intestinal canal conditions. |
| priorityDate | 2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.