http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102432639-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 |
| filingDate | 2011-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_465d2b410593b8510db50a283c31a08f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd683fe7a37129fab8ad027f9fdaaed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_166b19baf84df47bc87f9aca23b46f56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7a780e9de8092c03761d2e939a883c5 |
| publicationDate | 2013-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102432639-B |
| titleOfInvention | 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound and medicinal use thereof |
| abstract | The invention discloses a 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound and a medicinal use thereof. The 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound is a chiral 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate derivative. A result of a pharmacological experiment shows that the 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound has an obvious effect of inhibiting lung cancer cell proliferation; and lung cancer cell A549 inhibition activity of the 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound is superior to lung cancer cell H322 inhibition activity of the 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound. Therefore, the 1-(2-hydroxy-3-(phenylamino)propyl)-3-ferrocenyl-1H-pyrazole-5-ethyl formate compound as a novel ferrocenyl group-containing chiral pyrazole derivative has clinical application development prospects and has important meaning to antitumor drug development. |
| priorityDate | 2011-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.