http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102429872-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_405b2053821327b2aa7c45dd6bf9c984
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06
filingDate 2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d6f3b079844ac7b30629639c8330739
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43c8ad36e945af019a8e60f526b96fe8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c6f5c6163b88fa204e5c5c0b160ebf
publicationDate 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102429872-B
titleOfInvention Zileuton-containing membrane-controlled slow release pellets and preparation method thereof
abstract The invention discloses zileuton-containing membrane-controlled slow release pellets and a preparation method thereof. The zileuton-containing membrane-controlled slow release pellets contain quick release coated pellets and slow release coated pellets in a weight part ratio of 1:3-1:7, wherein the coated pellets consist of zileuton-containing medicated pellet cores and coatin layers wrapped outside the medicated pellet cores; and the weight part ratio of the medicated pellet cores to the coating layer is 5:1-15:1. The drup release rate of the zileuton-containing membrane-controlled slow release pellets is stable and controllable, and the clinical effectiveness is obviously improved; meanwhile, adverse effect occurrence of the gastrointestinal tract is also greatly reduced; and the pellets have a simple preparation process and high repeatability and are suitable for scale-up production.
priorityDate 2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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