| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adf225ca4a6bf6190b6a2763410d1ebf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-04 |
| filingDate |
2010-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74432c1795245905c670fbd70c9abe88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f7ffd44ec9378a92ae698d1604fa086 |
| publicationDate |
2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-102421892-B |
| titleOfInvention |
A diguanylate cyclase, method of producing the same and its use in the manufacture of cyclic-di-gmp and analogues thereof |
| abstract |
Described is a new standalone diguanylate cyclase polypeptide having a GGDEF motif and a mutated I-site that does not bind c-di-GMP. We demonstrate that the production yield of c-di-GMP and analogues was significantly increased by mutation of a conserved residue in the putative regulatory I-site. The synthesis of the c-di-GMP analogue, is reported. |
| priorityDate |
2009-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |