http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102417531-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1e5372cd866547f35c54ea4548bb02e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5db8c42def2abb6000a82834713f16c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204043944910a8d3f9cf682ff64af21c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a092c3c9648e1aa625d134b13750c4b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0129b4048aa43a5f521f42e0e956aa2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f46033537abbb0066ca35041037e672 |
| publicationDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102417531-B |
| titleOfInvention | Method for preparing azithromycin monohydrate |
| abstract | The invention mainly discloses a method for preparing an azithromycin monohydrate. The azithromycin monohydrate is prepared by crystallizing an azithromycin dihydrate or 9-deoxo-9a-aza-9a-homoerythromycin A which are taken as raw materials. The method comprises the following steps of: slowly adding the raw materials and water which is taken as an anti-solvent-out agent into an acetone-methanol mixed solvent at proper temperature, crystallizing, filtering, and baking under baking conditions to obtain the stable azithromycin monohydrate in which the residual quantity of the solvent is qualified. The method is easy to operate and high in yield (more than or equal to 95 percent), the quality is high (more than or equal to 98.5 percent), and the obtained product has a good crystal form, is high in fluidity and preparation adaptability, and can be industrially controlled easily. |
| priorityDate | 2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.