abstract |
The invention discloses a preparation method of an intermediate of rivaroxaban as shown in formula 6, which comprises the following steps: in a solvent, react compound 5 with deaminated benzyl protecting group. The invention also discloses a preparation method of rivaroxaban and an intermediate compound thereof. The preparation method of the invention has short route, low cost, easy-to-obtain raw materials and high yield, and is suitable for industrialized production. |