http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102406941-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
filingDate 2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e7d517df715c1714b42c6051ec164b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e804c6fdd7a9786c2d0607f2bccd9283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db11604e259deba733dd41b14e7b3e3f
publicationDate 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102406941-B
titleOfInvention Nanometer insoluble active component containing modified polyegline and preparation method thereof
abstract The invention discloses a nanometer insoluble active component containing modified polyegline and a preparation method thereof. The preparation comprises 1 part by weight of insoluble active component and 0.1-50 part by weight of modified polyegline, the particle size is 10-400 nm, and the preparation has good water solubility and does not contain any surface active agent or chemical cross-linking agent. Before intravenous injection, the preparation can be directly diluted with 0.9% sodium chloride or 5% glucose, long-time stability can be maintained during instillation, and the pharmacological effect is better than that of market injections. Safe and widely available modified polyegline is adopted as a stabilizing material of the nanometer insoluble active component, is biologically compatible, is easy to be excreted from human bodies and does not have cumulative toxicity for repeated application; drug carrying rate is high, and no propping agent or protecting agent is needed to be added into a freeze-dried preparation; and the process is simple and the preparation is applicable to industrial production.
priorityDate 2011-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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