http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102406941-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
filingDate | 2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8e7d517df715c1714b42c6051ec164b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e804c6fdd7a9786c2d0607f2bccd9283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db11604e259deba733dd41b14e7b3e3f |
publicationDate | 2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102406941-B |
titleOfInvention | Nanometer insoluble active component containing modified polyegline and preparation method thereof |
abstract | The invention discloses a nanometer insoluble active component containing modified polyegline and a preparation method thereof. The preparation comprises 1 part by weight of insoluble active component and 0.1-50 part by weight of modified polyegline, the particle size is 10-400 nm, and the preparation has good water solubility and does not contain any surface active agent or chemical cross-linking agent. Before intravenous injection, the preparation can be directly diluted with 0.9% sodium chloride or 5% glucose, long-time stability can be maintained during instillation, and the pharmacological effect is better than that of market injections. Safe and widely available modified polyegline is adopted as a stabilizing material of the nanometer insoluble active component, is biologically compatible, is easy to be excreted from human bodies and does not have cumulative toxicity for repeated application; drug carrying rate is high, and no propping agent or protecting agent is needed to be added into a freeze-dried preparation; and the process is simple and the preparation is applicable to industrial production. |
priorityDate | 2011-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.