| abstract |
The invention provides and there is P2Xn 3 or P2Xn 2/3 the compound of receptor antagonism.(in formula, Rn a , Rn b and Rn c , (a) Rn a with Rn b formation=Z, R togethern c for Rn 1c shown group, or (b) Rn b with Rn c form key together, Rn a for-Y-Rn 1a shown group, Rn 1a and Rn 1c be separately hydrogen atom, substituted or unsubstituted alkyl etc., Rn 2 and Rn 3 be separately substituted or unsubstituted aryl etc., Rn 4a and Rn 4b be separately hydrogen atom, substituted or unsubstituted alkyl etc. ,-X-is-N (Rn 5 )-etc., Rn 5 for hydrogen atom, substituted or unsubstituted low alkyl group etc., to be-O-etc., Z be-Y-=O etc., n is the integer of 0 ~ 4). |