http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102395559-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B63-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04 |
| filingDate | 2009-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102395559-B |
| titleOfInvention | Prepare the method for N-carbalkoxy Terleu |
| abstract | While pH value of solution being controlled in 9 ~ 13 scopes at use alkaline reagents, relative to Terleu, the N-alcoxyl carbonylating agent of more than 0.90 times mole less than 1.00 times moles is made to be used for Terleu in the presence of water preparing N-carbalkoxy Terleu, the N-carbalkoxy Terleu of available easy operation, good yield stable ground preparation high-quality.In addition, by making hydroxylate and this alkaline aqueous solution coexist with the solvent do not mixed with water when the alkaline aqueous solution of N-carbalkoxy-S-Leucine extracts, condition, good efficiency that just can be gentle be extracted.And by water yield during adjustment crystallization, just controlled fixture has the crystal formation of 2 kinds of polymorphous N-tertbutyloxycarbonyl-S-Leucines, thus industrially can stably prepare this compound. |
| priorityDate | 2009-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.