| abstract |
The invention belongs to the technical field of medicine, and specifically discloses a levofluoroquinolone C3 bisazole methide, and also discloses a preparation method of the levofluoroquinolone C3 bisazole methide and its application in the field of pharmacy. The chemical structural formula of levofluoroquinolone C3 bisazole methyl sulfide is shown in general formula I: General formula I, wherein, X is selected from any of O, S, -NH; Ar is selected from any of phenyl, phenyl with substituents, and heterocyclic aromatic hydrocarbon groups. The levofluoroquinolone C3 bisazole methyl sulfide provided by the present invention has a strong in vitro cytotoxic effect on experimental leukemia cancer cell lines, and has strong antitumor activity, and can be salt-formed with a human acceptable acid or with a pharmaceutical carrier. Mix to prepare antitumor drugs. |