http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102379861-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 |
| filingDate | 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b321e45be7c24a0c50e9eb8d817c0fdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c27a3e9feb6b3e95bdfff2313cc10512 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3de3ddc7a88ceb42f2e22ed68a251c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b0ccf0a2c6cda4341f7f50f9a76854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cdf496ae6eb377cb14818946ee59897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd05390b24c768430c89a6ba85926e51 |
| publicationDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102379861-B |
| titleOfInvention | Osmotic-pump timing sustained and controlled release capsule and preparation method thereof |
| abstract | The invention belongs to the technical field of medicinal preparations, and discloses an osmotic-pump timing sustained and controlled release capsule and a preparation method thereof. The capsule comprises a heterogeneous membrane capsule body, a non-water permeable capsule cap, and contents loaded inside. The contents comprise a pharmacologically active substance, a suspension and a penetration enhancer, and the weight percents are: 5%-30% of pharmacologically active substances, 40%-80% of suspensions, and 10%-50% of penetration enhancers; the heterogeneous membrane capsule body is an asymmetric bilayer membrane shell prepared by capsule material liquid and quenching liquid; the non-water permeable capsule cap is prepared by filling capsule liquid into a mold and volatilizing the liquid; the contents are directly loaded inside in a form of powder or particles; the capsule cap and the capsule body are sealed by the capsule material liquid; and a hole with a diameter of 0.3-0.5 mm is drilled on the top of the capsule cap. The capsule of the invention can be used to treat diseases with the characteristic of chronopharmacokinetics, and the system releases drugs with a constant speed by using osmotic pressure as power, which effectively avoid the peak-valley phenomenon of plasma concentration in the body, reduce side effect of the drugs, and improve patient compliance. |
| priorityDate | 2011-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.