http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102373181-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
| filingDate | 2010-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc5f444e9662b7ef8287f1062c35ac5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ac42b07d3d05bbaa5c84b9a48e91b4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b6e3326a702f28eac891479827e1a10 |
| publicationDate | 2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102373181-B |
| titleOfInvention | Swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particle, and preparation method and use thereof |
| abstract | The invention provides a swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particle. The swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particle contains a swine influenza virus stromatin M1, a swine influenza virus surface antigen hemagglutinin HA and an envelope fusion protein, wherein the envelope fusion protein contains an extramembranous domain of a main epitope of a porcine reproductive and respiratory syndrome virus protein GP5, and a transmembrane domain and an intramembranous domain of an influenza virus hemagglutinin HA; the extramembranous domain of the main epitope of the porcine reproductive and respiratory syndrome virus protein GP5 replaces an extramembranous domain of an end 5' of the swine influenza virus surface antigen hemagglutinin HA, and the length of the extramembranous domain of the main epitope of the porcine reproductive and respiratory syndrome virus protein GP5 is approximately equal to that of the replaced extramembranous domain; and the swine influenza virus surface antigen hemagglutinin HA and the porcine reproductive and respiratory syndrome virus protein GP5 are expressed on the surface of the swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particle simultaneously. The invention also provides a bivalent vaccine for preventing swine influenza and blue ear disease. The bivalent vaccine contains the swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particles and adjuvants. The invention also provides a preparation method of the swine influenza virus-porcine reproductive and respiratory syndrome virus mixed virus-like particle. |
| priorityDate | 2010-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 251.