http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102372673-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_970cbd224e39671e32a57c3bf5f6d3d0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
filingDate | 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97a410cae0a03555e3435f5fb795a9d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13367b1eb371af759521812f6bf9691a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cb326cd5c92bc92a744fbd9aa84a652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4249ee2e6a42ed3047402f6f0388444 |
publicationDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102372673-B |
titleOfInvention | Blonanserin crystallization and preparation method thereof |
abstract | The invention provides a 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5, 6, 7, 8, 9, 10-hexahydrocycloocta [b] pyridine (Blonanserin) crystallization and a preparation method thereof. The method includes the following steps: 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5, 6, 7, 8, 9, 10-hexahydrocycloocta [b] pyridine (Blonanserin) is heated to be dissolved in the mixture of ethanol, n-butyl alcohol, tertiary butanol, isobutyl alcohol, petroleum ether, butyl acetate, ethanol and isopropanol, and the Blonanserin crystallization is then obtained by way of recrystallization. The Blonanserin crystallization prepared by the method is safe, low in toxicity and stable for light, wet and heat, and is convenient to produce and store. Meanwhile, the invention also provides a drug combination containing the Blonanserin crystallization as an antipsychotic drug. |
priorityDate | 2010-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.