http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102370649-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02f24694b4445e31254823f04656311e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2010-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4bd0ecb5c805458902d7d7d932f6cb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b79ebf74971911a5cd1c41b6e09959b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a14aafc8cd667149290c2eb4743b10f |
publicationDate | 2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102370649-B |
titleOfInvention | Formula of YycG histidine kinase activity for inhibiting bacterial signal transduction system |
abstract | The invention, belonging to the technical field of biology, relates to a preparation for inhibiting YycG histidine kinase activity of a bacterial signal transduction system, particularly relates to a bacterial YycG histidine kinase inhibitor containing micro-molecular compound 3-(5-(5-(3,4-methylenedioxy phenyl)-6-ethoxy formoxyl-7-phenyl-5H-thiazolo[3,2-a]piperidine-3-keto-2-vinyl)-2-furyl)benzoic acid, especially an inhibitor of YycG protein of the signal transduction system of gram-positive bacteria. The bacterial YycG histidine kinase inhibitor disclosed herein has inhibiting effect on YycG protein in a staphylococcus epidermidis signal transduction system, can inhibit the growth of gram-positive bacteria and inhibit the biofilm formation of staphylococcus epidermidis. The inhibitor can be used for preparing medicines for treating diseases caused by gram-positive bacteria, and can be prepared into disinfectant for medical instruments or medical implements. |
priorityDate | 2010-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 561.