http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102363622-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 |
| filingDate | 2011-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c7dddfcd5cc85a3f216ff37c7c08c32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8115eed99d6a74bd86665224d0bb9fa2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe8ddb46afe9a812e48b23aba632e0e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46114458adff8dab300955ed7469915a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6837d5fcd1060b073fe0d46735cc634c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cacea91e4c7aea45aa8d48e419e10cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2590eca80a5b5eadbbe8e404216214a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9ba439480fdfb78ef2091efec6d23f8 |
| publicationDate | 2014-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102363622-B |
| titleOfInvention | Compound and preparation method and use thereof |
| abstract | The invention relates to the field of pharmaceutical chemistry and discloses a compound and a preparation method and use thereof. The compound of the invention has a structure shown by a formula I, and is formed by the Friedel-Crafts reaction of a compound of a formula II and a compound of a formula III at -78 to 0 DEG C under the catalytic action of sliver ionic reagent and alkaline salt under an anoxybiotic condition. In the invention, under the catalytic action of the silver ionic reagent and alkaline salt, the structural units of the compound of the formula III and the flustramine of the compound of the formula II are coupled by the Friedel-Crafts reaction to form the brand new antitumor formula compound of the formula I. The compound of the formula I has obvious activity for various tumor cells and can be used in preparation of medicines for treating cancers. |
| priorityDate | 2011-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.