http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102362861-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1a8e83bc78770ac96051cdb77665a71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2011-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_620dc2a110e4057389f1596f37a286f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfa3e9d7aa5e7d34246fba32a1fbc4db |
| publicationDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102362861-B |
| titleOfInvention | Hollow composite nanoparticle with core-shell structure and preparation method thereof |
| abstract | The invention relates to a hollow composite nanoparticle with a core-shell structure and a preparation method thereof. The nanoparticle comprises, successively from inside to outside, a cationic liposome, PLGA, a neutral liposome, and a biodegradable polymer at the outermost layer. The preparation method comprises the following steps: carrying out two-step emulsification, carrying out post-treatment comprising curing, cleaning and the like on a particle, and storing the finally prepared nanoparticle in a buffer solution. The method which is novel, simple and easy to operate belongs to a physical embedding method, so no damage is generated to embedded siRNA; and the particle size is constant; carriers prepared through the method have a large embedding amount and a high embedding rate (78-82%), so the carriers have wide application prospects in the medicament release field. |
| priorityDate | 2011-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.