| abstract |
The present invention discloses a compound of formula (I) or a pharmaceutically acceptable salt thereof: where Q is or R 1 is an alkyl group or an aryl group, and the aryl group is optionally substituted with one to five substituents independently selected from the following: C 1 to C 6 alkyl, C 1 to C 4 haloalkyl, -OR 4 and/or or halogen; and R 2 , R 3 , R 4 and n are as defined herein. The present invention also discloses methods of using the compounds as selective agonists of G protein-coupled receptor S1P1 , and pharmaceutical compositions comprising the compounds. These compounds are useful in treating, preventing or slowing the progression of diseases or disorders in various therapeutic areas, such as autoimmune and vascular diseases. |