| abstract |
The present disclosure provides a series of compounds of formula (I) that reduce β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's disease and other diseases affected by β-amyloid peptide (β-AP) production , wherein A is a 5- or 6-membered heteroaromatic ring containing 1-3 heteroatoms independently selected from nitrogen, oxygen and sulfur; B is selected from phenyl and pyridyl, D is selected from formula (II), E It is selected from C ie alkyl, C de cycloalkyl, benzyl, phenyl and 5-6 membered heteroaromatic rings containing one or two nitrogen atoms. |