http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102351884-B

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filingDate 2007-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_189beddaebd257334afadc93dd8fedd0
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publicationDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-102351884-B
titleOfInvention Process for the crystallisation of cefadroxil
abstract The present invention relates to a process for the preparation of cefadroxil in crystal form, comprising a) adding an aqueous solution of cefadroxil to a crystallisation vessel and a titrant to keep a pH in the crystallisation vessel of between 7 to 9; and b) lowering the pH in the crystallisation vessel to a value of between 5 and 6.5 to obtain a suspension of the ss-lactam compound in crystal form. The invention further relates to cefadroxil in crystal form obtainable by the process according to the present invention. The invention also relates to cefadroxil in crystal form with a CIE b value of below 12 when stored at a temperature of 25 DEG C for at least 1 month.
priorityDate 2006-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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