| abstract |
The invention belongs to the technical field of platelet aggregation inhibiting drugs, and provides isoxazole derivatives with a structure shown in the formula I and pharmaceutically acceptable salts thereof. In the formula I, R<1> is acetoxyl; R<2> is H, methyl or ethyl; and R<3> and R<4> are H, methyl, isopropyl, cyanomethyl, ethoxycarbonyl or chlorophenyl. The invention also relates to a preparation method of the compounds, and simultaneously discloses pharmaceutical compositions with the compounds or pharmaceutically acceptable salts of the compounds as the active effective ingredient, and application of the pharmaceutical compositions used as platelet aggregation inhibiting drugs. |