| abstract |
The invention belongs to the technical field of anti-platelet aggregation drugs, and provides isoxazole derivatives with the structure of formula I and pharmaceutically acceptable salts thereof, wherein R1 is: acetoxy; R2 is: hydrogen, methyl, ethyl base; R 3 and R 4 are: hydrogen, methyl, isopropyl, cyanomethyl, ethoxycarbonyl, chlorobenzene. The present invention also relates to a preparation method of the above compound, and discloses a pharmaceutical composition using the compound or a pharmaceutically acceptable salt thereof as an active ingredient, and their application as an anti-platelet aggregation drug. |