http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102351870-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 |
| filingDate | 2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd19f61e81a83bc726e0362a4e4820b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2cfd8f3d7460cf21a68d59c537ea581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64ef899c3167c2f1002d044acf526179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53a618601a5640a8883e80d5e0d1ecb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13ae82feebc1c4dcb6dfa32869db11a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c3b9ee4bbb1818e2a084bcf9955261c |
| publicationDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102351870-B |
| titleOfInvention | Method for preparing benzacridine derivative and application of benzacridine derivative as anti-cancer medicine |
| abstract | The invention belongs to the fields of medicines and chemical industry, and discloses a benzacridine derivative, a method for preparing the benzacridine derivative and application of the benzacridine derivative as an anti-cancer medicine. The benzacridine derivative has a structural formula shown in the specifications, wherein R1 and R2 is CH3O or OCH2O; n is 2 or 3; R3 is NHR4 or NR5; R4 is C1 to C6 alkyl, C3 to C6 naphthenic base, aromatic naphthenic base, aromatic ring base, aromatic heterocyclic radical and the like; and R5 is C1 to C6 alkyl, C3 to C6 naphthenic base, pyrrolidyl, piperidyl, piperazinyl, morpholinyl and the like. The benzacridine derivative has a strong inhibiting effect on deoxyribonucleic acid (DNA) expression of c-myc proto-oncogenes, an obvious inhibiting effect on various cancer cell lines, low toxicity on normal cells, and wide application space in the aspect of preparing the anti-cancer medicine. |
| priorityDate | 2011-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.