http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102351834-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71bfc04ef9fa00bef2087bb1b2497993 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-86 |
| filingDate | 2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6de74e104a606eac02937b23566c92f8 |
| publicationDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102351834-B |
| titleOfInvention | An economical, practical and environmentally friendly method for preparing mangiferin |
| abstract | The invention relates to the field of medicinal chemistry, and discloses a two-step method for preparing mangiferin aglycone, namely: adding 2-bromo-4,5-dimethoxybenzoic acid into 1,2-dichloroethane, adding chlorine Add sulfoxide, heat and reflux for 1 hour, add zinc chloride and 3,5-dimethoxyphenol and stir, continue heating at 40-80°C for 2-4 hours, distill 1,2-dichloroethane solvent under reduced pressure , add 10-30% sodium hydroxide aqueous solution by mass percentage, continue to heat and reflux for 2-3 hours to generate 1,3,6,7-tetramethoxyxanone; 1,3,6,7-tetramethyl Oxyxanone is added to ethylene glycol solvent, hydrochloric acid is added, and the reaction is heated under reflux for 3-5 hours to obtain mangiferin aglycone. Compared with the prior art, the preparation method of the present invention has short synthesis route, fewer steps, simple operation, high yield, cheap and easy-to-obtain raw materials, safety and low toxicity, environmental friendliness, convenient industrial production, and high economical efficiency. Practical value. |
| priorityDate | 2011-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.