http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102336719-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea798fc3adcc043e14d17a55a73e3b92 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-06 |
| filingDate | 2011-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dfea1b4b518d792aecc154c7a806237 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bbf028149b77184e56b94b3ab406a4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e0c3d6c5434adf69d5592e7269591de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f793e4a5f9e72331e304c68c91ba77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa5dbec9a33b45f859fa40f1ba835e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83051c07dcc59718c67a376d479a887f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1247c869b411f8c80df9db676f8661f4 |
| publicationDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102336719-B |
| titleOfInvention | Method for synthesizing 1,2,3-triazole compounds by utilizing sila-alkyne compounds |
| abstract | The invention relates to a method for synthesizing 1,2,3-triazole compounds by utilizing sila-alkyne compounds. The method comprises the following steps of: adding a sila-alkyne compound, an azide, an organic solvent and a desilication reagent to a reactor, and reacting at the temperature of 10-100 DEG C; and after the reaction is finished, adding an inorganic acid aqueous solution for acidifying until the pH value presents acidity, extracting multiple times with ethyl acetate, washing organic phase with saturated saline solution, drying with anhydrous sodium sulfate, removing the solvent under reduced pressure, and separating and purifying the residue through recrystallizing or column chromatography to obtain a product. The method has the advantages that the process is simple; the sila-alkyne compounds are used as raw material, thereby avoiding the use of heavy metals; the raw materials and reagents are available; the method has the characteristics of mild reaction condition, no need of carrying out oxygen-free protection on the reaction system, high reaction selectivity, high yield and the like; and the method has important practical significance. |
| priorityDate | 2011-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.