http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102335423-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af2cbc7af07abca038bffe4aa4e99ba4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
| filingDate | 2007-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b6cdeae8ae8952fbfaab90823160f66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ce7de9e0836fe72a05d3995b92b6fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_998989974bc4fc9ead2e1754e2a1d773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97e54ec74fd184605064c8ecbe3b1507 |
| publicationDate | 2014-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102335423-B |
| titleOfInvention | II type adenovirus live vector recombinant vaccine of dog for showing lyssa virus protective antigen by using spike |
| abstract | The invention discloses an II type adenovirus live vector recombinant vaccine of a dog for showing a lyssa virus protective antigen by using a spike and relates to a recombinant vaccine for respectively showing the lyssa virus protective antigen or an epitope by using characteristics of different structure proteins of the II type adenovirus of the dog. A lyssa virus protective antigen gene or a nucleotide sequence for expressing the epitope is inserted in a hydrophobic locus spike of the structure protein gene of the II type adenovirus of the dog, so that an exogenous antigen or epitope is subjected to fusion expression with the structure proteins of the II type adenovirus of the dog on the surface of the adenovirus. After toxic substances are eliminated from the recombinant vaccine, the closed isolated feeding for a test animal is carried out and the food searching and pathogenic conditions of the test animal are observed and recorded. The result shows that the dog subjected to oral administration and intramuscular injection of any recombinant vaccine can resist attack of virulent strain and has a survival rate of over 90 percent. |
| priorityDate | 2007-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.