abstract |
Compounds of the present invention are compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein: is a double bond and X is C; or is a single bond and X is N, CH, or CQR 1 ; and wherein: n is 1-10; R is H or QR 1 ; each R' is independently selected from H and QR 1 ; each Q is independently selected from a bond , CO, NH, S, SO, SO or O; each R 1 is independently selected from C 1 -C 10 alkyl, C 2 -C 10 alkenyl, C 2 -C 10 alkynyl, substituted or unsubstituted Aryl or heteroaryl, acyl, C 1 ‑C 10 cycloalkyl, halogen, C 1 ‑C 10 alkylaryl or C 1 ‑C 10 heterocycloalkyl; L is nitrogen-containing heteroaryl; and W is a zinc chelating residue. The compounds are useful in therapy. |