| abstract |
Formula I compound, wherein A, An n 1 , Rn n 1 , Rn n 7a , Rn n 7b , Rn n 8 And Rn n 10 All have the meaning that provides in the specification sheets of the present invention, be the DP2 acceptor inhibitor, can be used for treatment and epidemic prevention disease, allergic disease is such as asthma, rhinallergosis and atopic dermatitis with other is by PGDn n 2 (PGDn n 2 ) inflammatory diseases that mediated.Formula I compound also can be used for treating disease or the medical conditions that relates to the Th2T cell via producing IL-4, IL-5 and/or IL-13. |