http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102321635-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4cca08abbd98276cd2b11d967a4f67e |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 |
filingDate | 2011-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f42160391908c3c74e180cfefdc968fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_123b6731e20a7c4862c52d74b906920f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a07d83cb0c9142e63fd27421ef0cc59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98ffc202198be6ad8bfad9b1cf366569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86e243933f16164192d74e64b8eede3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be6e1aef939b7ccd93929827deda3547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44b0b59967f3d92bdfa86d6506807a7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eae5ea6c8fc020f785dc4c0beffc12f9 |
publicationDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102321635-B |
titleOfInvention | Preparation method for human papillomaviral empty capsid particles, and products thereof |
abstract | The present invention discloses a preparation method for human papillomaviral (HPV) empty capsid particles, and products thereof. The preparation method comprises: (1) inserting main capsid protein gene of the human HPV empty capsid particles or a combination coexpressed from the main capsid protein gene of the human HPV empty capsid particles and the secondary capsid protein gene of the human HPV empty capsid particles into baculovirus genome to construct recombinant baculovirus; (2) transfecting an insect host or insect cells through the constructed recombinant baculovirus; (3) culturing the transfected insect host or the transfected insect cells, collecting and purifying the expressed antigen to obtain the human HPV empty capsid particles. According to the preparation method, the baculovirus expression system is adopted for safely and efficiently producing the human HPV empty capsid particles in a bombyx mori bioreactor; with adopting the method provided by the present invention, the production cost for the human HPV empty capsid particles can be significantly reduced; the method has advantages of safety, high performance, less energy consumption, low cost, and the like. |
priorityDate | 2011-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 775.