http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102294018-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2011-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102294018-B |
| titleOfInvention | A kind of adriamycin and annexin V-conjugate and its preparation method and application |
| abstract | The invention belongs to biological technical field, and in particular to it is a kind of have with the annexin V and its Variant molecules of phosphatidylserine binding ability and coupling, the preparation method and application of anticancer drugs, doxorubicin, with 1 ethyl（3 dimethylaminopropyls）Phosphinylidyne diimmonium salt hydrochlorate and N hydroxy thiosuccinimides are that crosslinking agent is coupled with adriamycin, and the method for preparing soluble conjugate.The conjugate of preparation has more preferable antitumor activity, is laid a good foundation for further research anti-tumor drugs targeting and its application. |
| priorityDate | 2011-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.