http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102286369-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7610cef0de1410bf21e1e54706e208a |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-36 |
| filingDate | 2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3037226b6b87e2af9a4e4022614b091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a271de0a05ab878d8a06a8b1282a27e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15b6ee19d8149b2768f1f72cc6d6e902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21a939508212209af1c3f458cfe5d5ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8bec5638f50080801538c935d46a2e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd7396b0257811b9fb7db6f6ce562097 |
| publicationDate | 2013-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102286369-B |
| titleOfInvention | Microorganism fermentation process scaling-up platform technique |
| abstract | The invention provides a microorganism fermentation process scaling-up platform technique. In the process of fermentation, symbolic metabolites are chosen to reflect the growing state of microorganisms and the condition of fermentation medium, and by controlling the change of the symbolic metabolites, and combined with hydromechanics to calculate, design and improve the size and structure of a stirring reactor, the gas holdup is increased and the concentration of the symbolic metabolites is decreased; and fermentation conditions are optimized and the fermentation process is scaled up. The technique is applied in the production of glutathione and S-adenosine-L-methionine and the coproduction of glutathione and ergosterol by brewing yeast fermentation and the production of hyaluronic acid by streptococcus zooepidemicus fermentation. The symbolic metabolites are ethanol, glycerin, lactic acid and acetic acid. The technique ensures that the concentration of ethanol in the high-density aerobic fermentation of yeast is less than 0.5 percent and that the concentration of lactic acid as the symbolic metabolite in the production of hyaluronic acid by bacterial fermentation is less than 3 percent. The technique is easy to operate, and the automation degree is high; and the application range is wide, and the technique can be used in the yeast system as well as the bacteria system. |
| priorityDate | 2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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