abstract |
The invention relates to a pyrrolidine boronate ester (boronate ester) DDP-IV inhibitor, which plays a beneficial role in the treatment and prevention of diseases involving dipeptidyl peptidase-IV, such as diabetes, especially type 2 diabetes, tumors or other diseases. The invention relates to pharmaceutical compositions comprising these compounds and their use in the prevention or treatment of these diseases in which dipeptidyl peptidase-IV is involved. |