http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102283807-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate | 2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102283807-B |
| titleOfInvention | Preparation method and application's method of liquid precursor liposome |
| abstract | The present invention relates to a kind of preparation method of liquid precursor liposome, this preparation method is dissolved in medicine, matrix material and hydroxypropul starch in propane diols jointly, add before use the aqueous solution to form drug-loaded liposome, or medicine and matrix material are dissolved in propane diols jointly, after adding before use the aqueous solution that contains hydroxypropul starch, form drug-loaded liposome, in preparation process, by the usage ratio of matrix material concentration or change propane diols and the aqueous solution in change propane diols, drug-loaded liposome size control is arrived in micron or nanometer range. This preparation method is easy, and entrapment efficiency is high, and particle diameter is controlled, is conducive to biomembrane barrier in medicine transdermal, mucous membrane or body, and performance long-acting, is suitable for medicine scope wide, is particularly suitable for the medicine that amphipathic difference or molecular weight are large. The invention still further relates to the application process of above-mentioned liquid lipidosome, can be applicable to the multiple formulations such as spray, gel, injection, meet the needs of mucous membrane, skin, the surface of a wound, cavity part or whole body therapeutic. |
| priorityDate | 2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.